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ETC / RX - Systemic anti-infective agents - Opecipro


Ciprofloxacin 500 mg


Gastrointestinal tract infections, urinary tract and renal infections, gonorrhoea and genital tract infections, skin and skin structure infections, bone and joint infections, respiratory tract infections, ear-nose-throat infections, oral cavity and dental infections, gyneacological and obstetric infections, sepsis, biliary tract infections, abdominal infections (peritonitis), prophylaxis in infection.


Uncomplicated urinary tract infections 250 mg twice daily.
Complicated urinary tract infections: 500 mg twice daily.
Severe respiratory tract infections and osteomyelitis. 750 mg twice daily.
Other infections: 500mg twice daily
A single dose of 250mg is recommended in acute gonorrhoea for one day.

Opecipro therapy in continued for 7 days in the treatment of renal and urinary tract infections. Osteomyelitis is treated for 2 months. Duration of therapy for other infections is from 7 to 14 days. In the treatment of infections caused by susceptible streptococci, duration of therapy should be at least 10 days.

For most infections therapy should be continued for 72 hours after clinical and bacteriological therapy is obtained.


Patients with a history of hypersensitivity to ciprofloxacin, nalidixic acid and to other quinolones.
Pregnancy and lactation.


In patients with a history of convulsion, Opecipro should be used after a convulsive therapy has been provided.
Ciprofloxacin may cause dizziness, their individual susceptibility to these adverse effects should be determined before operating a motor vehicle or machinery.
Opecipro is not recommended to use in the children till the end of skeletal growth is complete


Nausea, diarrhea, vomiting, abdominal pain.
Dizziness, headache, insomnia, irritability.
Pruritus, urticaria, angioedema, erythema nodosum.


Antacids containing magnesium and calcium, decrease absorption of Opecipro. It is suggested that Opecipro should be given to the patients 2 hours before or after antacids administration.
Concomitant use of Opecipro and theophylline causes increased serum theophylline concentrations.
Patients receiving Opecipro should be well hydrated and should be instructed to drink fluids liberally.


Box of 2 blisters x 7 coated caplets.
Box of 1 bottle x 100 coated caplets.