{"id":988,"date":"2026-05-19T09:51:55","date_gmt":"2026-05-19T02:51:55","guid":{"rendered":"https:\/\/opv.vn\/?post_type=product&p=988"},"modified":"2026-05-19T09:51:55","modified_gmt":"2026-05-19T02:51:55","slug":"glucoform-500-850","status":"publish","type":"product","link":"https:\/\/opv.vn\/en\/glucoform-500-850\/","title":{"rendered":"Glucoform 500, 850"},"content":{"rendered":"<p><strong>TH\u00c0NH PH\u1ea6N:<\/strong><\/p>\n<p>Metformin HCl: 500mg &amp; 850mg<\/p>\n<p>Cho m\u1ed9t vi\u00ean n\u00e9n.<\/p>\n<div>\n<hr size=\"2\" width=\"100%\" \/>\n<\/div>\n<p><strong>CH\u1ec8 \u0110\u1ecaNH:<\/strong><\/p>\n<p>Metformin l\u00e0 thu\u1ed1c \u0111i\u1ec1u tr\u1ecb \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng nh\u00f3m biguanid \u0111\u01b0\u1eddng u\u1ed1ng. Thu\u1ed1c \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb b\u1ec7nh \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng th\u1ec3 kh\u00f4ng ph\u1ee5 thu\u1ed9c insulin m\u00e0 kh\u00f4ng ki\u1ec3m so\u00e1t \u0111\u01b0\u1ee3c b\u1eb1ng ch\u1ebf \u0111\u1ed9 \u0103n ki\u00eang.<br \/>\nMetformin c\u00f3 th\u1ec3 d\u00f9ng nh\u01b0 \u0111\u01a1n li\u1ec7u ph\u00e1p ho\u1eb7c k\u1ebft h\u1ee3p v\u1edbi thu\u1ed1c nh\u00f3m sulfonylurea, thu\u1ed1c \u1ee9c ch\u1ebf men alpha-glucosidase, ho\u1eb7c v\u1edbi insulin.<\/p>\n<div>\n<hr size=\"2\" width=\"100%\" \/>\n<\/div>\n<p><strong>C\u00c1CH D\u00d9NG-LI\u1ec0U D\u00d9NG:<\/strong><\/p>\n<p><strong>Ng\u01b0\u1eddi l\u1edbn:<\/strong><\/p>\n<p><strong><em>\u0110\u01a1n li\u1ec7u ph\u00e1p:<\/em><\/strong><\/p>\n<ul>\n<li>Kh\u1edfi \u0111\u1ea7u u\u1ed1ng 500 mg, ng\u00e0y 2 l\u1ea7n, ngay sau b\u1eefa \u0103n s\u00e1ng v\u00e0 t\u1ed1i. N\u1ebfu c\u1ea7n c\u00f3 th\u1ec3 t\u0103ng li\u1ec1u t\u1eeb t\u1eeb \u0111\u1ebfn 500 mg\u00a0 x 3 l\u1ea7n\/ng\u00e0y sau 1 ho\u1eb7c 2 tu\u1ea7n.<\/li>\n<li>Li\u1ec1u t\u1ed1i \u0111a l\u00e0 2500 mg\/ng\u00e0y.<\/li>\n<\/ul>\n<p><strong><em>K\u1ebft h\u1ee3p v\u1edbi thu\u1ed1c nh\u00f3m sulfonylurea, thu\u1ed1c \u1ee9c ch\u1ebf men alpha-glucosidase:<\/em><\/strong><\/p>\n<ul>\n<li>B\u00e1c s\u0129 s\u1ebd quy\u1ebft \u0111\u1ecbnh li\u1ec1u d\u00f9ng c\u1ee7a m\u1ed7i thu\u1ed1c.<\/li>\n<\/ul>\n<p><strong><em>K\u1ebft h\u1ee3p v\u1edbi Insulin:<\/em><\/strong><\/p>\n<ul>\n<li>Ti\u1ebfp t\u1ee5c li\u1ec1u insulin hi\u1ec7n h\u00e0nh.<\/li>\n<li>Kh\u1edfi \u0111\u1ea7u u\u1ed1ng 500 mg, ng\u00e0y 1 l\u1ea7n. N\u1ebfu c\u1ea7n, c\u00f3 th\u1ec3 t\u0103ng li\u1ec1u t\u1eeb t\u1eeb \u0111\u1ebfn 500 mg x 2 l\u1ea7n\/ng\u00e0y sau 1 ho\u1eb7c 2 tu\u1ea7n cho \u0111\u1ebfn khi \u0111\u1ea1t \u0111\u01b0\u1ee3c ki\u1ec3m so\u00e1t \u0111\u01b0\u1eddng huy\u1ebft.<\/li>\n<\/ul>\n<p><strong>Tr\u1ebb em t\u1eeb 10 \u0111\u1ebfn 17 tu\u1ed5i:<\/strong><\/p>\n<ul>\n<li>Li\u1ec1u l\u01b0\u1ee3ng v\u00e0 c\u00e1ch d\u00f9ng s\u1ebd \u0111\u01b0\u1ee3c quy\u1ebft \u0111\u1ecbnh b\u1edfi b\u00e1c s\u0129.<\/li>\n<\/ul>\n<div>\n<hr size=\"2\" width=\"100%\" \/>\n<\/div>\n<p><strong>CH\u1ed0NG CH\u1ec8 \u0110\u1ecaNH:<\/strong><\/p>\n<ul>\n<li>M\u1eabn c\u1ea3m v\u1edbi metformin.<\/li>\n<li>Nhi\u1ec5m toan ceton, ti\u1ec1n h\u00f4n m\u00ea do ti\u1ec3u \u0111\u01b0\u1eddng.<\/li>\n<li>Suy th\u1eadn (creatinin huy\u1ebft thanh l\u1edbn h\u01a1n ho\u1eb7c b\u1eb1ng 1,5 mg\/dL \u1edf nam gi\u1edbi, l\u1edbn h\u01a1n ho\u1eb7c b\u1eb1ng 1,4 mg\/dL \u1edf n\u1eef gi\u1edbi) ho\u1eb7c thanh th\u1ea3i creatinin b\u1ea5t th\u01b0\u1eddng<\/li>\n<li>Suy gan, b\u1ec7nh tim m\u1ea1ch, b\u1ec7nh h\u00f4 h\u1ea5p n\u1eb7ng v\u1edbi gi\u1ea3m oxygen huy\u1ebft, b\u1ec7nh ph\u1ed5i thi\u1ebfu oxygen m\u1ea1n t\u00ednh.<\/li>\n<li>Suy tim sung huy\u1ebft, tr\u1ee5y tim m\u1ea1ch, nh\u1ed3i m\u00e1u c\u01a1 tim c\u1ea5p t\u00ednh.<\/li>\n<li>Nhi\u1ec5m khu\u1ea9n n\u1eb7ng, nhi\u1ec5m khu\u1ea9n huy\u1ebft.<\/li>\n<li>Ng\u1ed9 \u0111\u1ed9c r\u01b0\u1ee3u c\u1ea5p, ho\u1ea1i th\u01b0, thi\u1ebfu dinh d\u01b0\u1ee1ng.<\/li>\n<li>Ph\u1ee5 n\u1eef c\u00f3 thai ho\u1eb7c \u0111ang cho con b\u00fa.<\/li>\n<\/ul>\n<div>\n<hr size=\"2\" width=\"100%\" \/>\n<\/div>\n<p><strong>L\u01afU \u00dd V\u00c0 TH\u1eacN TR\u1eccNG:<\/strong><\/p>\n<ul>\n<li>Metformin c\u00f3 th\u1ec3 g\u00e2y n\u00ean ho\u1eb7c th\u00fac \u0111\u1ea9y vi\u1ec7c kh\u1edfi ph\u00e1t t\u00ecnh tr\u1ea1ng nhi\u1ec5m toan lactic. T\u1ea7n su\u1ea5t n\u00e0y c\u00f3 th\u1ec3 gi\u1ea3m nh\u1edd theo d\u00f5i ch\u1eb7t ch\u1ebd nh\u1eefng y\u1ebfu t\u1ed1 nguy c\u01a1, ch\u1ee9c\u00a0 n\u0103ng th\u1eadn v\u00e0 s\u1eed d\u1ee5ng li\u1ec1u metformin th\u1ea5p nh\u1ea5t m\u00e0 hi\u1ec7u qu\u1ea3.<\/li>\n<li>\u0110\u00e1nh gi\u00e1 ch\u1ee9c n\u0103ng th\u1eadn tr\u01b0\u1edbc khi b\u1eaft \u0111\u1ea7u \u0111i\u1ec1u tr\u1ecb v\u00e0 h\u1eb1ng n\u0103m.<\/li>\n<li>N\u00f3i chung, n\u00ean tr\u00e1nh d\u00f9ng metformin cho b\u1ec7nh nh\u00e2n c\u00f3 b\u1ec7nh l\u00fd gan.<\/li>\n<li>Ph\u1ea3i ng\u01b0ng d\u00f9ng metformin ngay t\u1ee9c kh\u1eafc khi c\u00f3 hi\u1ec7n di\u1ec7n gi\u1ea3m oxy m\u00e1u c\u1ea5p, b\u1ec7nh l\u00fd tim c\u1ea5p t\u00ednh, m\u1ea5t n\u01b0\u1edbc ho\u1eb7c nhi\u1ec5m khu\u1ea9n.<\/li>\n<li>N\u1ed3ng \u0111\u1ed9 glucose th\u1ea5p c\u00f3 th\u1ec3 l\u00e0m b\u1ea1n ph\u1ea3n \u1ee9ng ch\u1eadm v\u00e0 \u1ea3nh h\u01b0\u1edfng t\u1edbi kh\u1ea3 n\u0103ng l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c. U\u1ed1ng r\u01b0\u1ee3u c\u00f3 th\u1ec3 l\u00e0m cho t\u00ecnh tr\u1ea1ng n\u00e0y t\u1ec7 h\u01a1n. Tuy nhi\u00ean, b\u1ea3n th\u00e2n metformin kh\u00f4ng \u1ea3nh h\u01b0\u1edfng l\u00ean kh\u1ea3 n\u0103ng l\u00e1i xe ho\u1eb7c v\u1eadn h\u00e0nh m\u00e1y m\u00f3c.<\/li>\n<li>N\u00ean t\u1ea1m ng\u01b0ng li\u1ec7u ph\u00e1p metformin khi ti\u1ebfn h\u00e0nh b\u1ea5t c\u1ee9 ph\u1eabu thu\u1eadt n\u00e0o (ngo\u1ea1i tr\u1eeb c\u00e1c ph\u1eabu thu\u1eadt nh\u1ecf kh\u00f4ng k\u00e8m theo h\u1ea1n ch\u1ebf \u0103n ho\u1eb7c u\u1ed1ng).<\/li>\n<li>Ph\u1ea3i t\u1ea1m ng\u01b0ng \u0111i\u1ec1u tr\u1ecb v\u1edbi metformin 2-3 ng\u00e0y tr\u01b0\u1edbc khi chi\u1ebfu ch\u1ee5p X-quang c\u00f3 s\u1eed d\u1ee5ng c\u00e1c ch\u1ea5t c\u1ea3n quang n\u1ed9i m\u1ea1ch ch\u1ee9a iod, v\u00e0 trong 48 gi\u1edd sau khi chi\u1ebfu ch\u1ee5p v\u00e0 ch\u1ec9 d\u00f9ng tr\u1edf l\u1ea1i sau khi \u0111\u00e1nh gi\u00e1 l\u1ea1i ch\u1ee9c n\u0103ng th\u1eadn th\u1ea5y b\u00ecnh th\u01b0\u1eddng.<\/li>\n<li>C\u00e1c t\u00e1c \u0111\u1ed9ng l\u00ean m\u1ea1ch m\u00e1u l\u1edbn: Kh\u00f4ng c\u00f3 nghi\u00ean c\u1ee9u l\u00e2m s\u00e0ng n\u00e0o thi\u1ebft l\u1eadp \u0111\u01b0\u1ee3c b\u1eb1ng ch\u1ee9ng thuy\u1ebft ph\u1ee5c c\u1ee7a vi\u1ec7c gi\u1ea3m nguy c\u01a1 tr\u00ean m\u1ea1ch m\u00e1u l\u1edbn c\u1ee7a metformin ho\u1eb7c b\u1ea5t k\u1ef3 thu\u1ed1c ch\u1ed1ng \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng n\u00e0o kh\u00e1c.<\/li>\n<li>Th\u1eadn tr\u1ecdng khi s\u1eed d\u1ee5ng metformin cho ng\u01b0\u1eddi l\u1edbn tu\u1ed5i.<\/li>\n<li>Tr\u1ebb em d\u01b0\u1edbi 10 tu\u1ed5i: T\u00ednh an to\u00e0n v\u00e0 c\u00e1ch d\u00f9ng hi\u1ec7u qu\u1ea3 ch\u01b0a \u0111\u01b0\u1ee3c thi\u1ebft l\u1eadp.<\/li>\n<\/ul>\n<div>\n<hr size=\"2\" width=\"100%\" \/>\n<\/div>\n<p><strong>T\u00c1C D\u1ee4NG KH\u00d4NG MONG MU\u1ed0N:<\/strong><\/p>\n<ul>\n<li>Th\u01b0\u1eddng g\u1eb7p: Ch\u00e1n \u0103n, bu\u1ed3n n\u00f4n, n\u00f4n, ti\u00eau ch\u1ea3y, \u0111\u1ea7y h\u01a1i, kh\u00f3 ti\u00eau.<\/li>\n<li>\u00cdt g\u1eb7p: Lo\u1ea1n s\u1ea3n m\u00e1u, thi\u1ebfu m\u00e1u b\u1ea5t s\u1ea3n, thi\u1ebfu m\u00e1u tan huy\u1ebft, gi\u1ea3m ti\u1ec3u c\u1ea7u, m\u1ea5t b\u1ea1ch c\u1ea7u h\u1ea1t. Nhi\u1ec5m toan lactic l\u00e0 m\u1ed9t bi\u1ebfn ch\u1ee9ng hi\u1ebfm g\u1eb7p nh\u01b0ng tr\u1ea7m tr\u1ecdng.<\/li>\n<\/ul>\n<p><strong>Th\u00f4ng b\u00e1o cho b\u00e1c s\u0129 nh\u1eefng t\u00e1c d\u1ee5ng kh\u00f4ng mong mu\u1ed1n g\u1eb7p ph\u1ea3i khi s\u1eed d\u1ee5ng thu\u1ed1c.<\/strong><\/p>\n<div>\n<hr size=\"2\" width=\"100%\" \/>\n<\/div>\n<p><strong>T\u01af\u01a0NG T\u00c1C THU\u1ed0C<\/strong><strong>:<\/strong><\/p>\n<ul>\n<li>Trong th\u1eddi gian \u0111i\u1ec1u tr\u1ecb \u0111\u1ed3ng th\u1eddi v\u1edbi c\u00e1c sulfonylurea ho\u1eb7c repaglinid, n\u00ean theo d\u00f5i \u0111\u01b0\u1eddng huy\u1ebft v\u00ec li\u1ec7u ph\u00e1p ph\u1ed1i h\u1ee3p c\u00f3 th\u1ec3 g\u00e2y h\u1ea1 \u0111\u01b0\u1eddng huy\u1ebft.<\/li>\n<li>Furosemid l\u00e0m t\u0103ng n\u1ed3ng \u0111\u1ed9 trong huy\u1ebft t\u01b0\u01a1ng v\u00e0 n\u1ed3ng \u0111\u1ed9 t\u1ed1i \u0111a trong m\u00e1u c\u1ee7a metformin.<\/li>\n<li>D\u00f9ng \u0111\u1ed3ng th\u1eddi v\u1edbi c\u00e1c thu\u1ed1c \u0111\u00e0o th\u1ea3i qua \u1ed1ng th\u1eadn (cimetidin, ranitidin, digoxin, morphin, quinin, trimethoprim, vancomycin) c\u00f3 th\u1ec3 l\u00e0m t\u0103ng nguy c\u01a1 nhi\u1ec5m toan acid lactic.<\/li>\n<li>Hi\u1ec7u qu\u1ea3 c\u1ee7a metformin c\u00f3 th\u1ec3 gi\u1ea3m khi d\u00f9ng \u0111\u1ed3ng th\u1eddi c\u00e1c thu\u1ed1c th\u00fac \u0111\u1ea9y t\u0103ng \u0111\u01b0\u1eddng huy\u1ebft nh\u01b0: Glucocorticosteroid, thu\u1ed1c k\u00edch th\u00edch b2 v\u00e0 thu\u1ed1c gi\u1ed1ng giao c\u1ea3m.<\/li>\n<\/ul>\n<div>\n<hr size=\"2\" width=\"100%\" \/>\n<\/div>\n<p><strong>TR\u00ccNH B\u00c0Y:<\/strong><\/p>\n<p>H\u1ed9p 1 v\u1ec9 x 10 vi\u00ean.<\/p>\n<p>H\u1ed9p 2 v\u1ec9 x 10 vi\u00ean.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>TH\u00c0NH PH\u1ea6N: Metformin HCl: 500mg &amp; 850mg Cho m\u1ed9t vi\u00ean n\u00e9n. CH\u1ec8 \u0110\u1ecaNH: Metformin l\u00e0 thu\u1ed1c \u0111i\u1ec1u tr\u1ecb \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng nh\u00f3m biguanid \u0111\u01b0\u1eddng u\u1ed1ng. Thu\u1ed1c \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb b\u1ec7nh \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng th\u1ec3 kh\u00f4ng ph\u1ee5 thu\u1ed9c insulin m\u00e0 kh\u00f4ng ki\u1ec3m so\u00e1t \u0111\u01b0\u1ee3c b\u1eb1ng ch\u1ebf \u0111\u1ed9 \u0103n ki\u00eang. Metformin c\u00f3 th\u1ec3 d\u00f9ng&#8230;<\/p>\n","protected":false},"featured_media":0,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"product_cat":[56],"product_tag":[],"class_list":["post-988","product","type-product","status-publish","hentry","product_cat-anti-diabetics"],"_links":{"self":[{"href":"https:\/\/opv.vn\/en\/wp-json\/wp\/v2\/product\/988","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/opv.vn\/en\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/opv.vn\/en\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/opv.vn\/en\/wp-json\/wp\/v2\/comments?post=988"}],"wp:attachment":[{"href":"https:\/\/opv.vn\/en\/wp-json\/wp\/v2\/media?parent=988"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/opv.vn\/en\/wp-json\/wp\/v2\/product_cat?post=988"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/opv.vn\/en\/wp-json\/wp\/v2\/product_tag?post=988"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}