M\u1ed7i vi\u00ean n\u00e9n bao phim ch\u1ee9a
\nHo\u1ea1t ch\u1ea5t:<\/p>\n
Acetaminophen\u2026.\u2026\u2026\u2026\u2026\u2026\u2026\u2026…500 mg<\/p>\n
Guaifenesin\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026…200 mg<\/p>\n
Phenylephrin HCl\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u202610 mg<\/p>\n
Dextromethorphan HBr\u2026\u2026\u2026\u2026…15 mg<\/p>\n
T\u00e1 d\u01b0\u1ee3c: Tinh b\u1ed9t ng\u00f4, tinh b\u1ed9t ti\u1ec1n h\u1ed3 h\u00f3a, povidon K30, natri starch glycolat, silic oxyd d\u1ea1ng keo khan, magnesi stearat, talc, acid citric khan, opadry AMB yellow.<\/p>\n
Vi\u00ean n\u00e9n bao phim, h\u00ecnh thu\u00f4n d\u00e0i, m\u00e0u v\u00e0ng, tr\u00ean hai m\u1eb7t vi\u00ean c\u00f3 in m\u00e0u \u0111en.<\/p>\n
Acetaminophen l\u00e0 ch\u1ea5t chuy\u1ec3n h\u00f3a c\u00f3 ho\u1ea1t t\u00ednh c\u1ee7a phenacetin, c\u00f3 t\u00e1c d\u1ee5ng gi\u1ea3m \u0111au b\u1eb1ng c\u00e1ch ng\u0103n ch\u1eb7n s\u1ef1 ph\u00e1t sinh xung \u0111\u1ed9ng g\u00e2y \u0111au \u1edf ngo\u1ea1i vi. Thu\u1ed1c c\u00f3 t\u00e1c d\u1ee5ng h\u1ea1 s\u1ed1t b\u1eb1ng c\u00e1ch \u1ee9c ch\u1ebf trung khu \u0111i\u1ec1u nhi\u1ec7t v\u00f9ng d\u01b0\u1edbi \u0111\u1ed3i.<\/p>\n
Guaifenesin l\u00e0 m\u1ed9t thu\u1ed1c long \u0111\u1eddm, c\u00f3 t\u00e1c \u0111\u1ed9ng th\u00fac \u0111\u1ea9y ho\u1eb7c l\u00e0m d\u1ec5 d\u00e0ng s\u1ef1 lo\u1ea1i b\u1ecf c\u00e1c ch\u1ea5t b\u00e0i ti\u1ebft t\u1eeb \u0111\u01b0\u1eddng h\u00f4 h\u1ea5p.<\/p>\n
Phenylephrin hydrochlorid l\u00e0 thu\u1ed1c gi\u1ed1ng th\u1ea7n kinh giao c\u1ea3m c\u00f3 t\u00e1c d\u1ee5ng tr\u1ef1c ti\u1ebfp l\u00ean c\u00e1c th\u1ee5 th\u1ec3 alpha1 adrenergic, g\u00e2y co m\u1ea1ch, gi\u1ea3m sung huy\u1ebft m\u0169i v\u00e0 xoang.<\/p>\n
Dextromethorphan hydrobromid l\u00e0 thu\u1ed1c gi\u1ea3m ho, t\u00e1c d\u1ee5ng l\u00ean trung t\u00e2m ho \u1edf h\u00e0nh t\u1ee7y. Thu\u1ed1c kh\u00f4ng c\u00f3 t\u00e1c d\u1ee5ng gi\u1ea3m \u0111au v\u00e0 \u00edt t\u00e1c d\u1ee5ng an th\u1ea7n.<\/p>\n
Acetaminophen \u0111\u01b0\u1ee3c h\u1ea5p thu nhanh t\u1eeb \u0111\u01b0\u1eddng ti\u00eau h\u00f3a v\u1edbi n\u1ed3ng \u0111\u1ed9 \u0111\u1ec9nh trong huy\u1ebft t\u01b0\u01a1ng \u0111\u1ea1t \u0111\u01b0\u1ee3c kho\u1ea3ng 30-60 ph\u00fat sau khi u\u1ed1ng. Acetaminophen \u0111\u01b0\u1ee3c ph\u00e2n b\u1ed1 trong h\u1ea7u h\u1ebft trong c\u00e1c m\u00f4 c\u1ee7a c\u01a1 th\u1ec3. Acetaminophen qua nhau thai v\u00e0 hi\u1ec7n di\u1ec7n trong s\u1eefa m\u1eb9. G\u1eafn k\u1ebft v\u1edbi protein huy\u1ebft t\u01b0\u01a1ng kh\u00f4ng \u0111\u00e1ng k\u1ec3 v\u1edbi n\u1ed3ng \u0111\u1ed9 \u0111i\u1ec1u tr\u1ecb th\u00f4ng th\u01b0\u1eddng nh\u01b0ng g\u1eafn k\u1ebft s\u1ebd t\u0103ng khi n\u1ed3ng \u0111\u1ed9 t\u0103ng. Th\u1eddi gian b\u00e1n h\u1ee7y c\u1ee7a Acetaminophen thay \u0111\u1ed5i t\u1eeb kho\u1ea3ng 1 \u0111\u1ebfn 3 gi\u1edd. Acetaminophen \u0111\u01b0\u1ee3c chuy\u1ec3n h\u00f3a ch\u1ee7 y\u1ebfu \u1edf gan v\u00e0 b\u00e0i ti\u1ebft trong n\u01b0\u1edbc ti\u1ec3u ch\u1ee7 y\u1ebfu d\u01b0\u1edbi d\u1ea1ng li\u00ean h\u1ee3p glucuronid (60-80%) v\u00e0 li\u00ean h\u1ee3p sulphat (20-30%). D\u01b0\u1edbi 5% \u0111\u01b0\u1ee3c b\u00e0i ti\u1ebft d\u01b0\u1edbi d\u1ea1ng Acetaminophen kh\u00f4ng \u0111\u1ed5i. M\u1ed9t ph\u1ea7n nh\u1ecf (d\u01b0\u1edbi 4%) \u0111\u01b0\u1ee3c chuy\u1ec3n h\u00f3a th\u00f4ng qua h\u1ec7 th\u1ed1ng cytochrom P450.<\/p>\n
Guaifenesin \u0111\u01b0\u1ee3c h\u1ea5p thu t\u1ed1t qua \u0111\u01b0\u1eddng ti\u00eau h\u00f3a. Thu\u1ed1c \u0111\u01b0\u1ee3c chuy\u1ec3n h\u00f3a v\u00e0 sau \u0111\u00f3 \u0111\u01b0\u1ee3c th\u1ea3i tr\u1eeb qua n\u01b0\u1edbc ti\u1ec3u.
\nPhenylephrin hydrochlorid \u0111\u01b0\u1ee3c h\u1ea5p thu b\u1ea5t th\u01b0\u1eddng qua \u0111\u01b0\u1eddng ti\u00eau h\u00f3a v\u00e0 tr\u1ea3i qua qu\u00e1 tr\u00ecnh chuy\u1ec3n h\u00f3a giai \u0111o\u1ea1n \u0111\u1ea7u \u1edf ru\u1ed9t v\u00e0 gan nh\u1edd enzym monoamine oxidase. Phenylephrin \u0111\u01b0\u1ee3c th\u1ea3i tr\u1eeb g\u1ea7n nh\u01b0 ho\u00e0n to\u00e0n qua n\u01b0\u1edbc ti\u1ec3u.
\nDextromethorphan hydrobromid \u0111\u01b0\u1ee3c h\u1ea5p thu nhanh qua \u0111\u01b0\u1eddng ti\u00eau h\u00f3a v\u00e0 thu\u1ed1c c\u00f3 t\u00e1c d\u1ee5ng trong v\u00f2ng 15 \u2013 30 ph\u00fat sau khi u\u1ed1ng, k\u00e9o d\u00e0i kho\u1ea3ng 6-8 gi\u1edd. Thu\u1ed1c \u0111\u01b0\u1ee3c chuy\u1ec3n h\u00f3a \u1edf gan v\u00e0 b\u00e0i xu\u1ea5t qua n\u01b0\u1edbc ti\u1ec3u d\u01b0\u1edbi d\u1ea1ng kh\u00f4ng \u0111\u1ed5i v\u00e0 c\u00e1c ch\u1ea5t chuy\u1ec3n h\u00f3a demethyl bao g\u1ed3m dextrophan, m\u00e0 c\u0169ng c\u00f3 t\u00e1c d\u1ee5ng gi\u1ea3m ho.<\/p>\n
Thu\u1ed1c \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh l\u00e0m gi\u1ea3m c\u00e1c tri\u1ec7u ch\u1ee9ng trong c\u1ea3m l\u1ea1nh v\u00e0 c\u1ea3m c\u00fam nh\u01b0:<\/p>\n
– S\u1ed1t – C\u00e1c c\u01a1n \u0111au – Nh\u1ee9c \u0111\u1ea7u<\/p>\n
– Ho – \u0110au h\u1ecdng – Sung huy\u1ebft m\u0169i (ngh\u1eb9t m\u0169i)<\/p>\n
– L\u00e0m lo\u00e3ng \u0111\u1eddm (ch\u1ea5t nh\u1ea7y) v\u00e0 l\u00e0m lo\u00e3ng d\u1ecbch ti\u1ebft ph\u1ebf qu\u1ea3n gi\u00fap d\u1ec5 ho h\u01a1n.<\/p>\n
– Ng\u01b0\u1eddi l\u1edbn v\u00e0 tr\u1ebb em t\u1eeb 12 tu\u1ed5i tr\u1edf l\u00ean: U\u1ed1ng 1 vi\u00ean, c\u00e1ch m\u1ed7i 6 gi\u1edd. Kh\u00f4ng d\u00f9ng qu\u00e1 6 vi\u00ean \/ 24 gi\u1edd.
\n– Tr\u1ebb t\u1eeb 6 tu\u1ed5i \u0111\u1ebfn 11 tu\u1ed5i: U\u1ed1ng \u00bd vi\u00ean c\u00e1ch m\u1ed7i 6 gi\u1edd. Kh\u00f4ng d\u00f9ng qu\u00e1 3 vi\u00ean \/ 24 gi\u1edd.<\/p>\n
– B\u1ec7nh nh\u00e2n \u0111\u01b0\u1ee3c bi\u1ebft qu\u00e1 m\u1eabn v\u1edbi b\u1ea5t k\u1ef3 th\u00e0nh ph\u1ea7n n\u00e0o c\u1ee7a thu\u1ed1c.<\/p>\n
– B\u1ec7nh nh\u00e2n \u0111ang d\u00f9ng c\u00e1c thu\u1ed1c IMAO (xem ph\u1ea7n t\u01b0\u01a1ng t\u00e1c thu\u1ed1c).<\/p>\n
– B\u1ec7nh nh\u00e2n c\u00f3 b\u1ec7nh m\u1ea1ch v\u00e0nh v\u00e0 cao huy\u1ebft \u00e1p n\u1eb7ng.<\/p>\n
– Thi\u1ebfu h\u1ee5t G6DP.<\/p>\n
– B\u1ec7nh nh\u00e2n b\u1ecb suy gan n\u1eb7ng.<\/p>\n
– Kh\u00f4ng d\u00f9ng cho tr\u1ebb em d\u01b0\u1edbi 6 tu\u1ed5i.<\/p>\n
Th\u1eadn tr\u1ecdng v\u00e0 c\u1ea3nh b\u00e1o \u0111\u1eb7c bi\u1ec7t khi s\u1eed d\u1ee5ng thu\u1ed1c ch\u1ee9a ho\u1ea1t ch\u1ea5t Acetaminophen:<\/p>\n
– B\u00e1c s\u0129 c\u1ea7n c\u1ea3nh b\u00e1o b\u1ec7nh nh\u00e2n v\u1ec1 c\u00e1c d\u1ea5u hi\u1ec7u c\u1ee7a ph\u1ea3n \u1ee9ng tr\u00ean da nghi\u00eam tr\u1ecdng nh\u01b0 h\u1ed9i ch\u1ee9ng Steven-<\/p>\n
Jonhson (SIS), h\u1ed9i ch\u1ee9ng ho\u1ea1i t\u1eed da nhi\u1ec5m \u0111\u1ed9c (TEN), hay h\u1ed9i ch\u1ee9ng Lyell, h\u1ed9i ch\u1ee9ng ngo\u1ea1i ban m\u1ee5n m\u1ee7 to\u00e0n th\u00e2n c\u1ea5p t\u00ednh (AGEP).<\/p>\n
Kh\u00f4ng d\u00f9ng v\u1edbi c\u00e1c thu\u1ed1c kh\u00e1c c\u00f3 ch\u1ee9a Acetaminophen.<\/p>\n
Tham kh\u1ea3o \u00fd ki\u1ebfn b\u00e1c s\u0129 n\u1ebfu b\u1ea1n c\u00f3 b\u1ec7nh: Tim m\u1ea1ch, b\u1ec7nh gan, ti\u1ec3u \u0111\u01b0\u1eddng, c\u01b0\u1eddng gi\u00e1p, ho ti\u1ebft r\u1ea5t nhi\u1ec1u \u0111\u00e0m, cao huy\u1ebft \u00e1p, suy th\u1eadn, t\u0103ng nh\u00e3n \u00e1p, ti\u1ec3u kh\u00f3 do ph\u00ec \u0111\u1ea1i tuy\u1ebfn ti\u1ec1n li\u1ec7t v\u00e0 ho m\u1ea1n t\u00ednh k\u00e9o d\u00e0i do h\u00fat thu\u1ed1c l\u00e1, do hen ph\u1ebf qu\u1ea3n, vi\u00eam ph\u1ebf qu\u1ea3n m\u1ea1n t\u00ednh ho\u1eb7c kh\u00ed ph\u1ebf th\u1ee7ng.<\/p>\n
Ng\u01b0ng d\u00f9ng thu\u1ed1c v\u00e0 tham kh\u1ea3o \u00fd ki\u1ebfn b\u00e1c s\u0129 n\u1ebfu:<\/p>\n
– C\u00f3 c\u00e1c tri\u1ec7u ch\u1ee9ng m\u1edbi.<\/p>\n
– \u0110\u1ecf da ho\u1eb7c s\u01b0ng ph\u00f9.<\/p>\n
– C\u01a1n \u0111au, sung huy\u1ebft m\u0169i, ho\u1eb7c ho n\u1eb7ng h\u01a1n ho\u1eb7c k\u00e9o d\u00e0i h\u01a1n 7 ng\u00e0y.<\/p>\n
– S\u1ed1t n\u1eb7ng h\u01a1n ho\u1eb7c k\u00e9o d\u00e0i h\u01a1n 3 ng\u00e0y.<\/p>\n
– C\u1ea3m gi\u00e1c b\u1ed3n ch\u1ed3n, ch\u00f3ng m\u1eb7t ho\u1eb7c m\u1ea5t ng\u1ee7.<\/p>\n
– Ho t\u00e1i ph\u00e1t ho\u1eb7c c\u00f3 k\u00e8m theo s\u1ed1t, ph\u00e1t ban da ho\u1eb7c nh\u1ee9c \u0111\u1ea7u k\u00e9o d\u00e0i.<\/p>\n
\u0110\u00e2y c\u00f3 th\u1ec3 l\u00e0 d\u1ea5u hi\u1ec7u c\u1ee7a b\u1ec7nh l\u00fd tr\u1ea7m tr\u1ecdng h\u01a1n.<\/p>\n
D\u00f9ng thu\u1ed1c trong th\u1eddi k\u1ef3 mang thai ho\u1eb7c cho con b\u00fa: N\u00ean tham kh\u1ea3o \u00fd ki\u1ebfn b\u00e1c s\u0129 tr\u01b0\u1edbc khi d\u00f9ng thu\u1ed1c n\u00e0y.<\/p>\n
T\u00e1c \u0111\u1ed9ng c\u1ee7a thu\u1ed1c khi l\u00e1i xe v\u00e0 v\u1eadn h\u00e0nh m\u00e1y m\u00f3c: D\u00f9ng th\u1eadn tr\u1ecdng khi \u0111ang l\u00e1i xe hay v\u1eadn h\u00e0nh m\u00e1y m\u00f3c.<\/p>\n
M\u1ed9t s\u1ed1 tr\u01b0\u1eddng h\u1ee3p d\u1ecb \u1ee9ng v\u1edbi thu\u1ed1c hi\u1ebfm x\u1ea3y ra nh\u01b0 ph\u00e1t ban da, ban \u0111\u1ecf, m\u00e0y \u0111ay, gi\u1ea3m ti\u1ec3u c\u1ea7u, suy gan. T\u00e1c d\u1ee5ng ph\u1ee5 kh\u00e1c c\u00f3 th\u1ec3 c\u00f3 l\u00e0 b\u1ed3n ch\u1ed3n, m\u1ea5t ng\u1ee7, t\u0103ng huy\u1ebft \u00e1p, lo\u1ea1n nh\u1ecbp tim, ch\u00f3ng m\u1eb7t, bu\u1ed3n n\u00f4n, n\u00f4n, k\u00edch \u1ee9ng d\u1ea1 d\u00e0y, run r\u1ea9y, ng\u01b0\u1eddi y\u1ebfu m\u1ec7t, \u1ea3o gi\u00e1c v\u00e0 kh\u00f3 th\u1edf.<\/p>\n
Th\u00f4ng b\u00e1o cho b\u00e1c s\u0129 nh\u1eefng t\u00e1c d\u1ee5ng kh\u00f4ng mong mu\u1ed1n g\u1eb7p ph\u1ea3i khi s\u1eed d\u1ee5ng thu\u1ed1c.<\/p>\n
– Kh\u00f4ng d\u00f9ng thu\u1ed1c n\u00e0y n\u1ebfu b\u1ea1n \u0111ang d\u00f9ng c\u00e1c thu\u1ed1c \u1ee9c ch\u1ebf men monoaminoxydase (IMAO) (m\u1ed9t v\u00e0i thu\u1ed1c \u0111i\u1ec1u tr\u1ecb tr\u1ea7m c\u1ea3m, b\u1ec7nh l\u00fd t\u00e2m th\u1ea7n hay c\u1ea3m x\u00fac, ho\u1eb7c b\u1ec7nh parkinson) ho\u1eb7c trong v\u00f2ng 2 tu\u1ea7n sau khi ng\u01b0ng d\u00f9ng c\u00e1c thu\u1ed1c IMAO. N\u1ebfu b\u1ea1n kh\u00f4ng bi\u1ebft r\u00f5 r\u1eb1ng thu\u1ed1c \u0111ang d\u00f9ng theo \u0111\u01a1n b\u00e1c s\u0129 c\u00f3 ch\u1ee9a IMAO hay kh\u00f4ng, ph\u1ea3i tham kh\u1ea3o \u00fd ki\u1ebfn c\u1ee7a b\u00e1c s\u0129 ho\u1eb7c d\u01b0\u1ee3c s\u0129 tr\u01b0\u1edbc khi d\u00f9ng thu\u1ed1c n\u00e0y.<\/p>\n
– C\u00e1c thu\u1ed1c ch\u1ed1ng co gi\u1eadt (g\u1ed3m phenytoin, barbiturat, carbamazepin), isoniazid c\u00f3 th\u1ec3 l\u00e0m t\u0103ng \u0111\u1ed9c t\u00ednh c\u1ee7a Acetaminophen tr\u00ean gan.<\/p>\n
– D\u00f9ng \u0111\u1ed3ng th\u1eddi phenylephrin v\u1edbi c\u00e1c amin c\u00f3 t\u00e1c d\u1ee5ng gi\u1ed1ng th\u1ea7n kinh giao c\u1ea3m c\u00f3 th\u1ec3 l\u00e0m gia t\u0103ng c\u00e1c t\u00e1c d\u1ee5ng kh\u00f4ng mong mu\u1ed1n v\u1ec1 tim m\u1ea1ch.<\/p>\n
– Phenylephrin c\u00f3 th\u1ec3 l\u00e0m gi\u1ea3m hi\u1ec7u l\u1ef1c c\u1ee7a c\u00e1c thu\u1ed1c ch\u1eb9n beta v\u00e0 c\u00e1c thu\u1ed1c ch\u1ed1ng t\u0103ng huy\u1ebft \u00e1p (bao g\u1ed3m debrisoquin, guanethidin, reserpin, methyldopa). R\u1ee7i ro v\u1ec1 t\u0103ng huy\u1ebft \u00e1p v\u00e0 c\u00e1c t\u00e1c d\u1ee5ng kh\u00f4ng mong mu\u1ed1n v\u1ec1 tim m\u1ea1ch c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c gia t\u0103ng.<\/p>\n
– Thu\u1ed1c ch\u1ed1ng tr\u1ea7m c\u1ea3m ba v\u00f2ng (amitriptylin, imipramin): C\u00f3 th\u1ec3 l\u00e0m t\u0103ng c\u00e1c t\u00e1c d\u1ee5ng kh\u00f4ng mong mu\u1ed1n v\u1ec1 tim m\u1ea1ch c\u1ee7a phenylephrin.<\/p>\n
– D\u00f9ng \u0111\u1ed3ng th\u1eddi phenylephrin v\u1edbi alcaloid n\u1ea5m c\u1ef1a g\u00e0 (ergotamin v\u00e0 methylsergid): L\u00e0m t\u0103ng ng\u1ed9 \u0111\u1ed9c n\u1ea5m c\u1ef1a g\u00e0.<\/p>\n
– D\u00f9ng \u0111\u1ed3ng th\u1eddi phenylephrin v\u1edbi digoxin: L\u00e0m t\u0103ng r\u1ee7i ro nh\u1ecbp \u0111\u1eadp tim kh\u00f4ng b\u00ecnh th\u01b0\u1eddng ho\u1eb7c \u0111au tim.<\/p>\n
– D\u00f9ng \u0111\u1ed3ng th\u1eddi phenylephrin v\u1edbi atropin s\u1ebd phong b\u1ebf t\u00e1c d\u1ee5ng ch\u1eadm nh\u1ecbp tim ph\u1ea3n x\u1ea1 do phenylephrin g\u00e2y ra.<\/p>\n
Acetaminophen:<\/p>\n
Tri\u1ec7u ch\u1ee9ng: Bu\u1ed3n n\u00f4n, n\u00f4n v\u00e0 \u0111au b\u1ee5ng (x\u1ea3y ra trong v\u00f2ng 24 gi\u1edd sau khi u\u1ed1ng). Sau 24 gi\u1edd, tri\u1ec7u ch\u1ee9ng c\u00f3 th\u1ec3 bao g\u1ed3m c\u0103ng \u0111au h\u1ea1 s\u01b0\u1eddn ph\u1ea3i, th\u01b0\u1eddng cho bi\u1ebft s\u1ef1 ph\u00e1t tri\u1ec3n c\u1ee7a ho\u1ea1i t\u1eed gan. T\u1ed5n th\u01b0\u01a1ng gan nhi\u1ec1u nh\u1ea5t trong kho\u1ea3ng 3 \u2013 4 ng\u00e0y sau khi u\u1ed1ng thu\u1ed1c qu\u00e1 li\u1ec1u d\u00f9ng v\u00e0 c\u00f3 th\u1ec3 d\u1eabn \u0111\u1ebfn b\u1ec7nh n\u00e3o, xu\u1ea5t huy\u1ebft, h\u1ea1 \u0111\u01b0\u1eddng huy\u1ebft, ph\u00f9 n\u00e3o v\u00e0 t\u1eed vong.<\/p>\n
C\u00e1ch x\u1eed tr\u00ed: X\u1eed l\u00fd t\u00f9y thu\u1ed9c v\u00e0o n\u1ed3ng \u0111\u1ed9 trong huy\u1ebft t\u01b0\u01a1ng. Acetylcystein b\u1ea3o v\u1ec7 gan n\u1ebfu d\u00f9ng trong kho\u1ea3ng 24 gi\u1edd k\u1ec3 t\u1eeb khi qu\u00e1 li\u1ec1u Acetaminophen (hi\u1ec7u qu\u1ea3 nh\u1ea5t n\u1ebfu d\u00f9ng trong kho\u1ea3ng 8 gi\u1edd). Li\u1ec1u u\u1ed1ng \u0111\u1ea7u ti\u00ean l\u00e0 140 mg\/kg (li\u1ec1u t\u1ea3i), sau \u0111\u00f3 cho ti\u1ebfp 17 li\u1ec1u n\u1eefa, m\u1ed7i li\u1ec1u 70 mg\/kg c\u00e1ch nhau 4 gi\u1edd m\u1ed9t l\u1ea7n. Than ho\u1ea1t ho\u1eb7c r\u1eeda d\u1ea1 d\u00e0y c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c th\u1ef1c hi\u1ec7n \u0111\u1ec3 gi\u1ea3m s\u1ef1 h\u1ea5p thu c\u1ee7a Acetaminophen.<\/p>\n
Phenylephrin hydrochlorid:<\/p>\n
Tri\u1ec7u ch\u1ee9ng: T\u0103ng huy\u1ebft \u00e1p, nh\u1ee9c \u0111\u1ea7u, c\u01a1n co gi\u1eadt, xu\u1ea5t huy\u1ebft n\u00e3o, \u0111\u00e1nh tr\u1ed1ng ng\u1ef1c, nh\u1ecbp tim ch\u1eadm.<\/p>\n
X\u1eed l\u00fd: N\u00ean \u0111i\u1ec1u tr\u1ecb tri\u1ec7u ch\u1ee9ng v\u00e0 h\u1ed7 tr\u1ee3.<\/p>\n
Dextromethorphan:<\/p>\n
Tri\u1ec7u ch\u1ee9ng: Bu\u1ed3n n\u00f4n, n\u00f4n, bu\u1ed3n ng\u1ee7, nh\u00ecn m\u1edd, rung gi\u1eadt nh\u00e3n c\u1ea7u, b\u00ed ti\u1ec3u ti\u1ec7n, tr\u1ea1ng th\u00e1i t\u00ea m\u00ea, \u1ea3o gi\u00e1c, m\u1ea5t \u0111i\u1ec1u h\u00f2a, suy h\u00f4 h\u1ea5p v\u00e0 co gi\u1eadt.<\/p>\n
X\u1eed l\u00fd: \u0110i\u1ec1u tr\u1ecb h\u1ed7 tr\u1ee3 v\u00e0 \u0111i\u1ec1u tr\u1ecb tri\u1ec7u ch\u1ee9ng. C\u00f3 th\u1ebf d\u00f9ng naloxon 2 mg ti\u00eam t\u0129nh m\u1ea1ch, d\u00f9ng l\u1eb7p l\u1ea1i n\u1ebfu c\u1ea7n.<\/p>\n
Qu\u00e1 li\u1ec1u guaifenesin kh\u00f4ng g\u00e2y ra c\u00e1c tri\u1ec7u ch\u1ee9ng nguy hi\u1ec3m \u0111\u1ebfn t\u00ednh m\u1ea1ng.<\/p>\n
Trong tr\u01b0\u1eddng h\u1ee3p d\u00f9ng qu\u00e1 li\u1ec1u, ph\u1ea3i li\u00ean h\u1ec7 ngay b\u00e1c s\u0129 hay \u0111\u1ebfn b\u1ec7nh vi\u1ec7n g\u1ea7n nh\u1ea5t.<\/p>\n
V\u1ec9 10 vi\u00ean, h\u1ed9p 1 v\u1ec9, 10 v\u1ec9 ho\u1eb7c 20 v\u1ec9.<\/p>\n
B\u1ea2O QU\u1ea2N: \u1edf nhi\u1ec7t \u0111\u1ed9 d\u01b0\u1edbi 30oC, n\u01a1i kh\u00f4 r\u00e1o, tr\u00e1nh \u00e1nh s\u00e1ng.<\/p>\n
H\u1ea0N D\u00d9NG: 36 th\u00e1ng k\u1ec3 t\u1eeb ng\u00e0y s\u1ea3n xu\u1ea5t. Kh\u00f4ng d\u00f9ng thu\u1ed1c khi qu\u00e1 h\u1ea1n s\u1eed d\u1ee5ng.<\/p>\n
NG\u00c0Y X\u00c9T L\u1ea0I T\u1edc H\u01af\u1edaNG D\u1eaaN S\u1eec D\u1ee4NG:<\/p>\n","protected":false},"excerpt":{"rendered":"
TH\u00c0NH PH\u1ea6N M\u1ed7i vi\u00ean n\u00e9n bao phim ch\u1ee9a Ho\u1ea1t ch\u1ea5t: Acetaminophen\u2026.\u2026\u2026\u2026\u2026\u2026\u2026\u2026…500 mg Guaifenesin\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026…200 mg Phenylephrin HCl\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u2026\u202610 mg Dextromethorphan HBr\u2026\u2026\u2026\u2026…15 mg T\u00e1 d\u01b0\u1ee3c: Tinh b\u1ed9t ng\u00f4, tinh b\u1ed9t ti\u1ec1n h\u1ed3 h\u00f3a, povidon K30, natri starch glycolat, silic oxyd d\u1ea1ng keo khan, magnesi stearat, talc, acid citric khan, opadry AMB yellow. M\u00d4 T\u1ea2 S\u1ea2N PH\u1ea8M Vi\u00ean n\u00e9n…<\/p>\n","protected":false},"featured_media":801,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"product_cat":[24,26],"product_tag":[],"class_list":["post-979","product","type-product","status-publish","has-post-thumbnail","hentry","product_cat-otc","product_cat-ameflu-cough-and-cold-preparations"],"_links":{"self":[{"href":"https:\/\/opv.vn\/en\/wp-json\/wp\/v2\/product\/979","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/opv.vn\/en\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/opv.vn\/en\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/opv.vn\/en\/wp-json\/wp\/v2\/comments?post=979"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/opv.vn\/en\/wp-json\/wp\/v2\/media\/801"}],"wp:attachment":[{"href":"https:\/\/opv.vn\/en\/wp-json\/wp\/v2\/media?parent=979"}],"wp:term":[{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/opv.vn\/en\/wp-json\/wp\/v2\/product_cat?post=979"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/opv.vn\/en\/wp-json\/wp\/v2\/product_tag?post=979"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}